Why Transdermal Supplementation is a Better Choice

January 19, 2021

Why Transdermal Supplementation is a  Better Choice

Why Transdermal Supplementation is a
Better Choice 

When it comes to a drug delivery system for magnesium oil or any supplement, the transdermal application is a better choice. Transdermal drug delivery is fast, efficient, and easy. But how do you know if it's right for you? This article will explore topical applications, what it is, and why it's the best choice for you.


What is Transdermal Supplementation?

Transdermal supplementation is using a transdermal patch or cream for the drug delivery. The design of human skin has a few different functions. First, it helps protect the body and provides a sturdy outer layer over muscles and fats.


Yet, it's also soft and able to soak up medicine when applied. However, to ensure that the medication is distributed efficiently, transdermal supplementation may have permeation enhancers. Drug permeation enhancers boost the ability of drug formation for more efficient skin penetration.


Men and women apply the transdermal patch, ointment, or cream directly to the skin and the body soaks up the ingredients immediately.


Why is Transdermal Supplementation a Better Choice?

A skin penetration study published by The National Library of Medicine  (NHI) outlined transdermal delivery as a way to administer a drug systematically across the skin. While the drug formulation, age, gender, skin conditions, and other factors come into play on how well the medicine soaks through the skin, transdermal formulations have some key benefits.


Targeted Application

Pharmaceutical sciences always mention transdermal application as a more targeted approach. Oral supplements must first go through the digestive tract before reaching the bloodstream. In essence, it's a whole-body approach that may not be specific to the area in pain.


While helping your whole body, a transdermal drug delivery system first goes to the area that needs it most. Why wait when you don't have to?


Faster Results

Transdermal delivery systems may provide quicker bodily results because they bypass the digestion system. It takes time for the body to break down food and medicine. Transdermal medicine may also eliminate the “first pass” possibility by the liver.


Oral or parenteral routes may encounter this problem, and the medicine absorption is slower or weakened. Transdermal medicine doesn't have this issue and enters the blood capillaries through the skin instead. The end result is a much faster way to deliver topical supplements.


No Swallowing or Irritation

Medication prescribed through oral administration may cause gastrointestinal irritation. Some people may find oral routes of administration upset their stomachs for a variety of reasons. The side effect may even outweigh the benefits of the medication.


Another issue that comes with oral medications is that some pills are hard to swallow. While this may seem like a small issue, if you have to take a horse-sized pill a few times a day for a period of time, the discomfort continues to add up. Transdermal delivery doesn’t have this concern at all.



Swallowing large pills can be painful, but other delivery methods, such as parenteral routes, can be even more painful. Parenteral routes include injection into the subcutaneous layers of fat or even muscle or spinal cord.


Transdermal creams are soothing instead. High-quality creams usually have other natural ingredients that the skin laps up. For example, an ointment containing lavender essential oil or coconut oil naturally soothes and rejuvenates the skin while being a carrier for the medicine throughout the body. The entire process is pain-free, natural, and soothing.


Steady Absorption

Transdermal application is fast, painless, and provides a steady absorption over time. While you may apply the topical cream once or twice a day, the formulation steadily moves throughout the body in a more timed-release process, ensuring you receive the best results.


Since it's a steady absorption, it removes the need to continuously reapply or have to remember to supplement throughout the day. It really is a better drug delivery choice.


Types of Transdermal Supplements

The popularity of transdermal supplements has soared in the last few years. Below are some common types of topical medications.


Transdermal Magnesiums

Magnesium is an essential mineral crucial for a few bodily functions. If you have a magnesium deficiency, you may have high blood pressure, weak bones, and heart problems, among other health concerns. Topical magnesium supplements applied to the skin can help boost levels for those with low levels.


Topical Hormone Creams

Replacement therapy using hormones, such as estrogen, progesterone, and testosterone, is another standard transdermal method. Low hormone levels can't be underestimated in how detrimental the effects have on your body. Natural hormone creams are a safe and effective way for pain management for a wide variety of health concerns.


Estrogen and Progesterone Creams

Formulations containing the sex hormone estrogen and progesterone are primarily used for women experiencing menopausal symptoms. However, men produce estrogen in smaller amounts and may need a supplement. Estrogen creams come in different varieties, such as estriol, and have been proven to boost estrogen levels.



DHEA or dehydroepiandrosterone is the "mother" hormone produced by the adrenal glands. It's considered the "mother" hormone because small amounts are converted to other hormones, such as estrogen or testosterone. Without DHEA, one would argue, you wouldn't have other vital hormones.


DHEA administered through the transdermal route is by far superior to a pill or tablet. It's become super popular in the last few years, and people who get their daily dose recommend it.


Melatonin Creams

Like DHEA, melatonin has become well-known in the last few years. Most people take a pill, but topical creams may provide better results. Melatonin is a hormone that encourages sleep. Applying melatonin directly to the skin an hour before bed encourages a peaceful slumber.


Is Transdermal Supplementation Right For Me?

Topical remedies in the form of ointments, creams, gels, and bandages have been used for centuries. The transdermal revolution is not a new one, but the actual benefits have recently become more well known.


Traditionally, you may have taken a pill or been given a shot as the first choice. However, transdermal supplementation is the better choice. It provides fast, efficient relief without the side effects that come with other delivery systems. Call your doctor today to find out if transdermal supplementation is right for you.