What does estriol do in the body?

March 25, 2019

What does estriol do in the body?

What does estriol do in the body?

Estrogen is a sex hormone produced naturally in the body. Estrogen has three primary forms —estrone, estradiol, and estriol. Since estriol is the weakest type of estrogen, it’s often overlooked in women’s health. However, its weakness might very well be the female hormones strength.



What does estriol do in the body?

Estriol has the lowest concentration in the body of the three estrogens. When a woman isn’t pregnant, only small levels can be detected. Once pregnancy occurs, the uterus produces large amounts to help thicken the uterine lining to support a healthy nine months. The bioidentical hormone estriol is also the safest form of estrogen. The reason is that estriol is the weakest form of estrogen, but with this comes safety and few adverse effects.  

The  Women’s Health Initiative (WIH) published a study showing that patients taking hormone replacement therapy (estriol, estrone, and estradiol) had no higher risk for breast cancer than not receiving any treatment. Nevertheless, those who did use replacement therapy reported a decrease in symptoms of menopause and multiple sclerosis.

Estriol for Menopause relief

Studies show that estriol relieves menopausal symptoms such as vaginal dryness and hot flashes. Vaginal atrophy (dryness) makes sexual intercourse painful. The vagina tissue lacks moisture, and any friction causes searing pain. Applying estriol to the vagina tissue will moisten cell membranes, helping to lubricate and alleviate the pain. Estriol is also mild and won’t enter the bloodstream like other forms of estrogen, resulting in fewer side effects.


Estriol for Anti-aging
One of the benefits of estriol is anti-aging qualities. As you age, people become concerned about everything from bone loss to heart health. Multiple estrogen replacement therapy studies show that estriol has a positive effect on autoimmune conditions, thyroid health, weight gain, urinary tract infections, and other health concerns. All of which, when controlled, lead to healthy living. Although some of these same studies show that women had a slightly higher risk for blood clots and high blood pressure. Of course, this also depended on many factors including dosage, therapy mixture, and length of use.

Estriol for Beautiful Skin

Estriol helps promote skin rejuvenation and collagen growth. Skin tissues contain estrogen receptors that soak up the estriol. Collagen is responsible for the firmness and suppleness of skin.


Estriol Treatment

Many health care practitioners use estriol in conjunction with estradiol in hormone replacement therapy to relieve menopause symptoms and estrogen imbalances. Estradiol, nicknamed the fountain of youth, promotes healthy cell growth. Women have an abundance of estradiol before menopause. The onset of menopause causes estrone to increase and estradiol to decrease. Using estradiol and estriol hormone replacement therapy (Bi-EST) is a safe and effective way to treat hormonal health concerns.

Estriol Applications

Studies suggest that when estriol cream is administered topically little to no side effects occur.  You can purchase estriol creams without a prescription. When buying estriol creams look for an all natural professional grade cream made in a food and drug administration approved facility.

Breast cancer, endometrial cancer, and cardiovascular... : Menopause. (n.d.). Retrieved February 28, 2019, from https://journals.lww.com/menopausejournal/Citation/2018/01000/Breast_cancer,_endometrial_cancer,_and.5.aspx

Estrogen. (n.d.). Retrieved March 3, 2019, from https://www.womensinternational.com/portfolio-items/estrogen/

Estrogen | Hormone Health Network. (n.d.). Retrieved February 28, 2019, from https://www.hormone.org/hormones-and-health/hormones/estrogen

Harvard Health Publishing. (n.d.). By the way, doctor: Is vaginal estrogen safe? Retrieved February 28, 2019, from https://www.health.harvard.edu/newsletter_article/By_the_way_doctor_Is_vaginal_estrogen_safe

Using Vaginal Estrogen Doesn't Increase Breast Cancer Risk. (n.d.). Retrieved February 28, 2019, from https://www.breastcancer.org/research-news/vaginal-estrogen-not-linked-to-high-risk