





BIOBeauty Renew Night Cream – Max Strength Estriol .3% Cream with Retinol
- MAXIMUM STRENGTH NIGHT SUPPORT — Designed for evening use, this advanced strength .3% bioidentical E3 cream works overnight to help your skin appear renewed, rested, and radiant by morning.
- HELPS ENHANCE FIRMNESS & GLOW — Supports natural skin elasticity and tone so your complexion feels visibly smoother and more youthful.
- BIOIDENTICAL BEAUTY SCIENCE — Features a balanced blend of bioidentical-inspired E3 elements to promote harmony in your skin’s appearance and natural balance.
- NOURISHES WITH CLEAN ACTIVES — Infused with Retinol, vitamin E, hyaluronic acid, and plant-based antioxidants to help comfort and protect your skin from daily environmental stressors.
- LUXURIOUS NIGHTTIME TEXTURE — Rich yet lightweight formula absorbs beautifully without leaving residue, ideal as your final step before bed.
CREAMS
Bioidentical cosmetic creams are expertly formulated for maximum absorption into the body, offering natural support for common age-related ailments and deficiencies. Unlike pills or powders that must pass through the digestive tract and are often broken down before they can be fully effective, these creams deliver their beneficial ingredients directly through the skin.
OILS
Our oils are crafted with the highest quality ingredients, ensuring purity and safety. It's free from artificial preservatives, parabens, phenoxyethanol, and sulfates. Plus, it’s cruelty-free and never tested on animals, nor does it contain any animal-based ingredients.
*shake well before using
CAPSULES
Oral supplements capsules feature potent herbal ingredients, ideal for those elements that aren’t suitable for topicals but can greatly enhance health.
Frequently Asked Question
Bi-EST 5.0 is a professional-strength topical cream delivering 5 mg of bioidentical estrogen per pump—composed of 4 mg estriol (E3) and 1 mg estradiol (E2). It’s formulated for maximum transdermal absorption.
Estriol is considered a “weaker” estrogen but has been studied for beneficial effects on skin, urogenital tissue, and bone. Estradiol is the primary estrogen produced by the ovaries and plays a major role in regulating menstrual cycles, bone density, mood, and cardiovascular health.
Many women are drawn to bioidentical-inspired beauty products as a modern innovation in cosmetic science and skincare. This lotion is designed to help support outer beauty and enhance the look of youthful, radiant skin.
Because the formula includes bioidentical-inspired ingredients, please use with care and avoid this product if you have concerns about or have been advised against using products that may introduce systemic hormones into your body.
The Bi-EST blend is often used because:
- Estriol (E3) binds weakly to estrogen receptors and may act as a “gentle” estrogen with tissue-specific effects.
- Estradiol (E2) is the most potent estrogen and is crucial for bone, cardiovascular, and neurological health. The combination may provide symptom relief while potentially reducing risks associated with higher estradiol doses.
The main difference is strength per pump.
- Bi-EST 2.5 provides 2.5 mg total estrogen (2.0 mg estriol + 0.5 mg estradiol).
- Bi-EST 5.0 provides 5.0 mg total estrogen (4.0 mg estriol + 1.0 mg estradiol). That means Bi-EST 5.0 delivers double the estrogen dose compared to Bi-EST 2.5.
Estriol cream: Primarily tissue-specific; great for localized support like vaginal dryness or skin thinning, with minimal systemic estrogen exposure.
Bi-Est cream: Broader support; can help support hot flashes, mood, energy, skin, bone, and cardiovascular health, while still containing estriol for gentler tissue-specific benefits.
No—the strength of the cream is the same in both bottles. The 3.6 oz bottle uses a more precise pump mechanism, which allows for smaller, adjustable doses. This design is especially convenient for people who need to take half doses or slightly less, giving you more control over your daily regimen.
For optimal absorption, we recommend applying the cream after a shower, when your skin is clean and your pores are open. This helps maximize hormone delivery and effectiveness.
This cosmetic product contains bioidentical hormones, Estriol and Estradiol, which may affect hormone levels. For external use only.
Consult a qualified healthcare provider before use, especially if you are:
• Pregnant or nursing
• Under 18
• Taking medications
• Managing a hormone-sensitive condition
Stop use and seek medical advice if you experience unusual symptoms such as mood changes, menstrual irregularities, or skin irritation.
Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA.
Keep out of reach of children.