Is it OK to use progesterone cream everyday?

June 17, 2024

Is it OK to use progesterone cream everyday?

As middle-aged women seek ways to manage their health, many turn to natural solutions like progesterone cream to alleviate menopausal symptoms and achieve hormonal balance. But is it safe to use progesterone cream every day? This article explores the benefits, risks, and effectiveness of daily application, providing essential insights for women considering this therapy.

Understanding Progesterone Cream

Progesterone cream is a topical treatment used to supplement low progesterone levels, especially in peri and postmenopausal women. Natural progesterone creams are derived from plant sources like wild yam and are formulated to mimic the hormone produced by the body.

Benefits of Progesterone Cream

Progesterone cream offers numerous benefits, particularly for menopausal women:

  • Alleviation of Menopausal Symptoms: Daily application can help reduce hot flashes, night sweats, mood swings, and vaginal dryness.
  • Improved Hormonal Balance: By increasing progesterone levels, the cream helps balance estrogen and progesterone, which is crucial for reducing menopause-related symptoms.
  • Bone Density Support: Progesterone plays a role in maintaining bone density, which is particularly important for postmenopausal women.
  • Breast Health: Progesterone cream can help alleviate breast tenderness and support healthy breast tissue.
  • Skin Health: Applying progesterone cream on the skin can improve skin elasticity and hydration, benefiting overall skin health.

How to Use Progesterone Cream Safely and Effectively

  1. Consult Your Healthcare Provider: Before starting progesterone therapy, it’s essential to consult with a healthcare provider to determine the appropriate dose and usage. They can tailor the treatment to your specific needs and monitor hormone levels through blood tests.
  2. Application Sites: Common areas for applying progesterone cream include the inner thighs, wrists, forearm and abdomen. Rotating application sites can improve absorption and effectiveness.
  3. Dosage and Frequency: The recommended dose of progesterone cream varies, but it is often suggested to apply it once or twice daily. Following your healthcare provider’s instructions is crucial for achieving the best results.

Effectiveness of Progesterone Cream

Research supports the effectiveness of progesterone cream in managing menopausal symptoms. For instance, a double-blind, placebo-controlled study published in the National Library of Medicine found that topical progesterone significantly improved vasomotor symptoms like hot flashes and night sweats. Additionally, bioidentical progesterone creams are shown to be well-absorbed through the skin, providing a natural and effective alternative to oral progesterone.

Risks and Side Effects

While progesterone cream is generally considered safe, it’s important to be aware of potential risks and side effects:

  • Skin Irritation: Some women may experience irritation or allergic reactions at the application site.
  • Hormonal Imbalance: Overuse can lead to excessive progesterone levels, causing symptoms like weight gain, mood swings, and changes in menstrual cycles.
  • Interactions with Medications: Progesterone can interact with other medications, such as birth control pills and hormone replacement therapy. Always inform your healthcare provider about all medications and supplements you are taking.

Comparing Progesterone Cream to Other Forms

  • Progesterone Cream vs. Oral Progesterone: Topical progesterone is absorbed directly through the skin, bypassing the digestive system and potentially reducing the risk of side effects like nausea and liver stress. Oral progesterone, on the other hand, might be more effective for certain conditions but comes with a higher risk of systemic side effects.
  • Bioidentical Progesterone vs. Synthetic: Bioidentical progesterone, found in natural progesterone creams, is structurally identical to the body’s own hormone, potentially leading to better compatibility and fewer side effects compared to synthetic versions.


Using progesterone cream every day can be an effective and safe way to manage menopausal symptoms and achieve hormonal balance, especially when used under the guidance of a healthcare provider. It offers numerous benefits, from reducing hot flashes and night sweats to improving skin and bone health. However, it’s important to be aware of potential risks and to use the cream as directed.

For postmenopausal women and those experiencing symptoms of low progesterone, natural progesterone creams provide a promising alternative to traditional hormone replacement therapy. Always seek personalized medical advice to ensure the therapy is right for you and to monitor your progress safely.

To explore more about natural progesterone products and find the right solution for your needs, visit BIOLabs PRO and consult with your healthcare provider. Taking control of your health is within your reach with the right information and support.